Leica EM RAPID

Overview

The Leica EM RAPID milling device has been designed for Research on Active Pharmaceutical Ingredient Dispersal preparation for investigation with NIR spectrophotometry. With a tungsten carbide or diamond miller, pills can be decapsulated without any smearing caused by the pills'coating. A stereo microscope offers brilliant observation while milling the sample. The adjustable milling speed allows preparation of even fragile pills. Investigations on a defined layer can be performed by stepwise removal with pre-selected step advances and total advance indication. Multiple glass slide and single pill holders reduce the lead time to the NIR instrument. A low-noise extraction unit with a Hepa filter provides a silent and safe environment.

Key Features

• Decapsulation of pills without smearing effect
• Adjustable cutting speed between 300 - 20.000 rpm
• Defined layer removal in steps of 0.5, 1, 10 or 100 µm
• Brillliant ring LED top light and optimised back light illumination
• Low noise extraction and filtration unit with Hepa-filter

Single pill holder

The pill is mounted on the insert and clamped in the adaptor. After milling the insert can be placed directly in the NIR microscope. The insert dimensions are compatible with the Perkin Elmer tablet Autosampler

Multiple pill holder

For preparation and investigation of several tablets at once, a smart designed glassslide holder increases throughput considerably, allowing more than one pill to be milled simultaneously.